Depolarization: graded and action potential. Stimuli that increase membrane permeability to K^+ produce graded hyperpolarizations. A stronger stimulus produces a larger hyperpolarization. Stimuli that increase membrane permeability to Na^+ produce graded depolarizations. A stronger stimulus produces a larger depolarization. Some channels are voltage-gated: a depolarization causes more Na^+ channels to open. A depolarization that reaches the threshold (-55 mV) triggers positive feedback and causes a massive voltage change called action potential (30 mV).