_IMG_48_06aMembranePotentialA-L.jpg Neuron ionic gradients. The concentrations of Na+ and Cl- are higher in the extracellular fluid than in the cytosol of a neuron. The reverse is true for K+. These gradients are maintained by the sodium-potassium _FIG_../ch07/sodium-potassium_pump.html pump and cause the ions to diffuse back across the membrane and create a resting _SIZ_resting_potential.html potential.