Neural plasticity.

Activity in neurons can strengthen or weaken signaling at a synapse.

  • High activity of neuron N[1] leads to recruitment of more axon terminals from the same neuron. Lack of activity at N[2] leads to loss of synapses.
  • If two synapses are often active at the same time, the strength of the postsynaptic response may increase at both synapses, mediated by long-term potentiation.